CBD Oil for Nausea: A Safe Treatment for A Common Problem

Janet Miller

Janet Miller

November 19, 201917 min read

Nausea is a feeling of sickness with an inclination to vomit. The most common cause of nausea is a sharp decrease in the tone of the stomach with simultaneous tension in the area of the duodenum. It accompanies the imbalance of nerve impulses, and, as a consequence, the throwing of the contents of the duodenum into the stomach.

Using CBD oil for nausea has a long history. Two cannabis-based drugs hit the market, back in the 1980s, for managing the ailment, Marinol and Cesamet. These two drugs used a synthetic form of tetrahydrocannabinol (THC) to ease nausea in cancer and HIV patients.

Only people suffer either from nausea or vomiting for several reasons. Powerful medications are not always necessary to treat nausea or vomiting brought on by the flu or food poisoning. For this reason, natural, organic, non-intoxicating CBD oil has emerged to bridge the gap and offer anyone a safe, effective treatment for feeling ill.

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10 Score
EMPE Cbd Full Spectrum Hemp Oil Tincture Peppermint

EMPE Cbd Full Spectrum Hemp Oil Tincture Peppermint

EMPE Full-Spectrum Peppermint Oil is a full-spectrum CBD oil. It contains several phytocannabinoids and comes in four different strengths. The oil is for sublingual use, but consumers can also mix the liquid into foods or beverages.

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10 Score
Kat’s Naturals Metabolize Oil

Kat’s Naturals Metabolize Oil

Kat’s Naturals Metabolize is a CBD tincture mixed with other essential oils, terpenes, and vitamins. It promotes a healthier lifestyle along with a more balanced digestive system. The tincture is 100% THC-free.

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9.5 Score
Vape Additive by CBDfx

Vape Additive by CBDfx

This Vape Additive by CBDFx contains full-spectrum cannabidiol that users can add to any suitable vape device. This blend features only CBD mixed with propylene glycol and vegetable glycerin. There are three different strengths.

Learn More

The Top CBD Products for Nausea

The majority of the products mentioned here are best CBD oils for nausea intended for sublingual use. Although someone with nausea or similar symptoms may not find oral ingestion appealing, there are other ways to take these liquids. Each CBD for nausea description will also feature ingredient lists, other ingestion methods, and the cannabidiol content of each solution.

Best Full-Spectrum Oil for Nausea


EMPE Cbd Full Spectrum Hemp Oil Tincture Peppermint
10Score

#1 EMPE Cbd Full Spectrum Hemp Oil Tincture Peppermint

Highlights

  • Contains all-natural flavors
  • Contains other phytocannabinoids (full-spectrum)
  • Organically-grown
  • SIZE/VOLUME

    30mL

  • TOTAL CBD

    500mg, 1000mg, 1500mg, 2000mg

  • DOSE/SERVING

    One full dropper

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Pain relief
  • INGREDIENTS

    Hemp Derived Phytocannabinoids, Organic Hemp Oil, Peppermint Flavor and Vitamin E

An Extra-Strength CBD Tincture

EMPE manufactures its full-spectrum oil tincture from organically grown hemp. They use locally-sourced farms to create this oil that also features several cannabinoids. This blend comes flavored with subtle notes of peppermint to provide a balanced taste. This tincture comes in several strengths. Users can choose from the lowest concentration, 500mg, to the highest, which is 2000mg.

The bottle comes with a measured dropper inside so users can measure out the correct dosage. Empe recommends taking a full dropper worth of CBD solution, which is equal to one dose, holding it under the tongue and then swallowed. The tincture was third-party tested, and all lab reports show legal levels of THC. The tincture comes in a single 30ml bottle. Each strength level costs more than the previous one.


Best THC-Free Oil for Nausea


Kat’s Naturals Metabolize Oil
10Score

#1 Kat’s Naturals Metabolize Oil

Highlights

  • CO2-Extraction
  • Contains all-natural ingredients
  • 100% THC-Free
  • SIZE/VOLUME

    5mL, 15mL, 30mL

  • TOTAL CBD

    500mg/ounce

  • DOSE/SERVING

    1mL

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Bloating
    • Gas
    • Metabolism
    • Nausea
  • INGREDIENTS

    Critical CO2 Extracted CBD from American Grown Organic Hemp, Organic Hemp Seed Oil, Sustainably Sourced Organic Grapefruit, Organic Lemon, Organic Ginger, Organic Peppermint, and Organic Cinnamon Essential Oils

A Fruity Blend for an Upset Stomach

Kat’s Naturals Metabolize is a super blend of several essential oils and cannabidiol. Users can get the benefits not only of CBD, but of ginger, lemon, and cinnamon to calm an uneasy stomach. This blend was specially-formulated to promote digestive health. Users can take a few drops under the tongue, hold it there, and then ingest it. The mixture is rich in fatty acids, essential oils, and vitamins.

Kat’s Naturals Metabolize also contains terpenes that help promote a more balanced organism. This tincture comes from organically-grown, locally-sourced hemp plants. Kat’s uses supercritical C02-extraction to get its hemp extract. Metabolize is the rare cannabidiol tincture that comes in several bottle sizes rather than different strengths. Users can choose from three different sizes with a standard CBD content of 500mg.


Vape Additive by CBDfx
9.5Score

#2 Vape Additive by CBDfx

Highlights

  • Can be vaped or ingested sublingually
  • Contains full-spectrum cannabidiol
  • C02 Extracted
  • Loaded with terpenes, amino acids, and Omega 3, Omega 6
  • SIZE/VOLUME

    10mL

  • TOTAL CBD

    60mg, 120mg, 300mg

  • DOSE/SERVING

    10mL

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Stress relief
    • Anxiety
  • INGREDIENTS

    CBD (Cannabidiol), Propylene Glycol, and Vegetable Glycerin.

A Safe, High-Potency Vape Oil

This vape additive from CBDFx contains full-spectrum cannabidiol. The extract comes from organically-grown plants harvested in the USA. The blend features all the essential cannabinoids, amino, and fatty acids that users expect from a CBD product.

Users can vape the additive alone, or mix it into other flavors. CBDfx recommends blending it into fruity or dessert flavors, although vapers are free to choose their favorite. Users can also take this mixture sublingually. They can drop 1/2 or one full dropper into their mouths and hold it there for about thirty seconds before ingesting.

The additive/tincture comes in four different strengths. The base one is 60mg, and the highest is 300mg. Users can expect to pay more for the high-potency additive and less for the lower concentrations.



High-Potency Tincture Oil by CBDfx
10Score

#1 High-Potency Tincture Oil by CBDfx

Highlights

  • CO2-extracted
  • All-natural ingredients
  • High-concentration of hemp extract
  • SIZE/VOLUME

    30mL

  • TOTAL CBD

    1500mg

  • DOSE/SERVING

    1mL

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Insomnia
    • Anxiety
  • INGREDIENTS

    MCT coconut oil, full-spectrum hemp oil

Extra-Strength Tincture for Easy Ingestion

This high-concentration oil tincture from CBDfx offers users a full-spectrum, easy-to-use product. The hemp extract comes from 100% organic plants grown in the US. CBDfx uses CO2 extraction to get all its hemp extract so users can expect the highest purity. The lab reports all confirm that the product is free of harmful pesticides and other chemicals.

This tincture should be taken sublingually, with users dropping one or two drops under their tongue. For best results, users should hold the solution under their tongue for ten to twenty seconds. The liquid has only one CBD strength, which is 1500mg. The single 30ml bottle comes with a dropper for users to measure out their preferred dose.


Best Quality Oil


Diamond CBD Watermelon Bubblegum
10Score

#1 Diamond CBD Watermelon Bubblegum

Highlights

  • Made in the USA
  • Less than 0.3% THC
  • Ten different CBD strengths
  • SIZE/VOLUME

    30mL

  • TOTAL CBD

    25mg, 50mg, 100mg, 150mg, 250mg, 350mg, 450mg, 550mg, 1000mg, 1500mg

  • DOSE/SERVING

    One dropper full

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Sleep
    • Pain relief
    • Nausea
    • Upset stomach
  • INGREDIENTS

    Vegetable Glycerin, Propylene Glycol, Industrial Hemp Cannabidiol, Artificial Flavors.

A Tincture with a Fruity Pop!

Diamond CBD uses all-natural flavors and C02-extracted hemp extract in this oil tincture. Users can take the tincture sublingually or as an additive to vape juice. They can also vape the liquid alone as a vape juice. The two main flavor profiles of this tincture are watermelon and bubblegum. Diamond offers this tincture in ten different strengths. The lowest one contains only 50mg, and the highest of them all is 1500mg. The bottle comes in a single size, 30ml, and included is a dropper-style applicator to measure out dosage size. All lab reports show the tincture is 100% THC-free. Diamond uses both locally-sourced and overseas hemp, but all their plants are grown organically.


Lazarus Naturals French Vanilla Mocha Tincture
9.5Score

#2 Lazarus Naturals French Vanilla Mocha Tincture

Highlights

  • Vegan-friendly
  • Solvent-extracted (ethanol)
  • No GMOs
  • SIZE/VOLUME

    15mL, 30mL, 60mL

  • TOTAL CBD

    750mg, 1500mg, 3000mg, 6000mg

  • DOSE/SERVING

    One dropper full

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Sleep
    • Pain relief
    • Nausea
    • Upset stomach
  • INGREDIENTS

    Fractionated Coconut Oil, Hemp Extract, Naturally Derived Flavors

A Naturally-Sweetened, High-Potency Oil

Lazarus Naturals offers this high-potency CBD oil in several different strengths. Consumers can choose from three strengths, starting at 750mg going to 3000mg and ending at 6000mg. The oil uses all-natural ingredients and contains no artificial flavors. Lazarus Naturals uses organic vanilla and mocha extract to flavor this tincture for sublingual use. Coconut oil also features as an ingredient to make the cannabidiol more bioavailable.

There are about 50mg of CBD in every serving size, which is approximately 1ml. The 30ml bottle also comes with a graduated dropper so users can measure out an accurate dose. Lazarus Naturals uses full-spectrum hemp extract in this tincture. The lab report shows other cannabinoids present in the liquid, such as CBG and CBC.


PlusCBD Total Plant-Based Oil Drops
9Score

#3 PlusCBD Total Plant-Based Oil Drops

Highlights

  • Good for cooking and baking
  • Gluten-free
  • Perfect for vegans
  • SIZE/VOLUME

    30mL

  • TOTAL CBD

    300mg

  • DOSE/SERVING

    15 drops

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Anxiety
    • Energizing
  • INGREDIENTS

    Hemp oil, extra virgin olive oil, quillaja Saponaria

An All-Natural, Complex Oil

PlusCBD oil drops feature full-spectrum hemp extract along with other vital terpenes. This tincture comes unflavored and unsweetened so consumers can be sure they are only ingesting pure CBD. On top of pure CBD, this tincture also features important substances like vitamin E and chlorophyll. Another bonus of using no flavorings or sweeteners is that the oil is 100% vegan and contains no GMOs.

Despite having no added flavors, consumers will recognize a few flavor notes. The tincture does carry a distinct taste as users will note the earthy tones of olive oil and hemp. The tincture comes in a single 30ml bottle with a CBD strength of 300mg. Users can take a single dropper-full of liquid for each serving, which amounts to 4mg per serving.


CBD Oil: An Explainer

Cannabidiol, or CBD, is an active phytocannabinoid found in hemp and cannabis plants. While CBD is a relative of tetrahydrocannabinol (THC), the former has no intoxicating effects, unlike the latter. CBD is also non-habit-forming and non-toxic, so no one can either become dependent on it or overdose from taking too much.

Unlike THC, CBD has other, more beneficial properties. Scientists have found that cannabidiol can act as an:

For these reasons, cannabidiol has been much touted as a safe and organic alternative to other remedies for things like joint and muscle pain or anxiety and depression (keyword: alternative). No one should replace medications prescribed by a doctor with hemp extract unless medically directed to do so).

Producers extract the substance from live hemp plants (leaves, stalks, stems) using various methods (CO2 extraction, solvent-extraction, cold press). The result of the extraction process produces two substances:

  • The oil that contains many different cannabinoids (full-spectrum)
  • A powdery substance that contains only cannabidiol (isolate)

The difference between the two is that full-spectrum CBD offers users a more extensive range of helpful cannabinoids, each of which enhances the effects of the other (something known as the entourage effect). Isolate is pure CBD, which means that no other compounds, including THC, are present in its composition. Either compound can be found in commercially-available products like tinctures, sprays, capsules, and edible products.

Effects of CBD on Nausea

It is essential to understand how and why CBD oil can reduce feelings of nausea or prevent vomiting, to first uncover the science behind nausea and vomiting. First, nausea and vomiting are not the same things. While neither is comfortable, they are not illnesses. They are both, more likely, symptoms of an underlying malady or sickness.

Nausea – the uneasy feeling in your stomach that precedes (often, but not always) vomiting

Vomiting aka emesis – the forceful ejection of stomach materials via the mouth and esophagus

The relationship between the two is not always so linear. People can start vomiting without feeling nauseous (exposure to chemicals, foul odors, emotional stress), or they can feel nauseous without eventually vomiting (motion sickness, stomach ache).

While there are several reasons that people feel nauseous or begin vomiting, the discussion here is centered around the four principal areas of the body responsible for instigating the vomiting reaction:

  • The chemoreceptor trigger zone (CTZ)
  • The vestibular system (the inner ear)
  • The thalamus (inner brain)
  • The gastrointestinal system

The CTZ, aka “vomit center,” consists of the area postrema, which is one of the primary mechanisms that trigger nausea and vomiting, although not the only one. The CTZ and area postrema both receive signals from all over the body (the nervous system, gastrointestinal system) that can activate the process that leads to nausea and vomiting.

The area postrema also acts independently, though. It actively scans the bloodstream for harmful and foreign toxins. If it detects something toxic or poisonous (too much alcohol, or actual poison) it sends signals to other parts of the body (like your diaphragm or stomach) to expel it via vomiting.

What Is the Role That CBD Oil Plays in All This?

CBD for nausea is an agonist, meaning it activates specific receptors in the brain (5HT-3 receptors) that receive signals from other parts of the body to start the vomiting process. Activating these receptors blocks the other signals (the vomit signals) from reaching these areas in the CTZ that induce emesis or vomiting.

More than just block, CBD for nausea also reduces the frequency with which these receptors are transmitting, like turning down the volume on a loud noise. Studies on other mammals have shown it takes only twenty minutes or so, for a small amount of the compound (around 5mg) to take effect and reduce symptoms of nausea.

The Science Behind CBD

The reasons that CBD for nausea has such positive effects on this and many other bodily functions have to do with the human endocannabinoid system (ECS). The ECS is a system of neurotransmitters and receptors located throughout the body (spine, brain, nervous system). The ECS has an essential role in regulating things like mood, appetite, and pain-reception.

When someone takes CBD for nausea, it interacts with these cannabinoid receptors in different ways. To explain how this works, one need only look at how another cannabinoid, THC, interacts with the same receptors. THC binds itself to the CB1 and CB2 receptors. This bonding triggers intoxication, feelings of euphoria, motor impairment – all the classic signs of the “high” associated with THC.

CBD for nausea does not bind to or interact with the CB1 and CB2 receptors. It bonds to other transmitters producing different effects, like easing nausea or preventing emesis. In the words of one research paper on the ECS and CBD, “CBD has anxiolytic (anti-anxiety) properties and attenuates THC psychoactive effects.” So while the compound does not produce a high, it still has effects on the body, including minimizing the impact of THC.

Using CBD Oil for Nausea

People who experience regular vomiting or nausea should consult a physician. As stated before, nausea and vomiting are often symptoms of a more significant problem, so if they persist, go to a doctor. For instances of nausea or emesis that are not related to more severe sickness, people could administer a dropper-full of CBD tincture if they are feeling ill. They could also add a few drops to a cold or hot beverage, a meal, or some other edible item if they prefer that way.

Anti-Emetic Properties

No one is sure about the necessary dosage – the study above citing 5mg was performed on rats, and the hemp extract was injected – to relieve the feeling of nausea. People can start with the lowest dose possible and then experiment. As they feel their nausea dissipate, they can stop taking any higher dose.

Multiple studies have shown how only a small amount of CBD for nausea is necessary to produce positive, antiemetic effects. A study from the University of Colorado looking at the effects of cannabidiol on sleep and anxiety noted, “lower doses appear to elicit an adequate clinical response.

What CBD Products are Good to Treat Nausea?

The versatility of CBD for nausea is one of its main selling points. Producers take the oil or isolate and mix into a variety of different products. Depending on the reason a person wants to take hemp extract, some product options are better than others. For example, someone with joint or muscle pain might benefit more from a CBD cream than a gummy bear or edible items.

Despite all the products listed here being oils and tinctures, users could also make use of capsules, sprays, or even vape juice. If someone is feeling ill and is averse to eating or swallowing anything, vaping either CBD oil for nausea or a vape additive could help ease symptoms in a more palatable way.

How Much CBD Should I Take?

No one can say for sure what CBD dosage for nausea a person should take for any given purpose. Best CBD for nausea is not currently classified as a medication, so a doctor or healthcare professional could not provide such answers. If people want to use cannabidiol as a deterrent against nausea or vomiting, they should try the most fast-acting method of ingesting, which is vaping.
Even it can be effective to consume a 25mg of CBD. In diseases like cancer, or migraines, the dosage can be between 20 mg to 1000mg per day.

CBD vapor travels directly to the brain, which is also where the so-called vomit center is located. Whether a low, mid, or high-dose could potentially offset a nauseous feeling remains to be seen. Users should experiment with as many different dosages as possible to find their ideal dose.

What to Look for When Buying CBD Oil for Nausea

Whatever CBD for nausea a person chooses to take for whatever reason, they should first make sure the product and company adhere to the following:

  • Transparency – is the company open about where they source their hemp? Do they mention how the plant is farmed (organically, locally)?
  • Extraction – does the company state how they extract the compound?
  • Testing – does the company perform lab tests on all their products? Do they use an independent, third-party lab to perform the analysis?
  • Lab reports – does the company display the lab results of all their products? Do they make them clearly visible? Do the lab reports match the claims made by the manufacturer (THC-free, pesticide-free, etc.)?

Holding manufacturers to these standards is an excellent way to ensure you are getting a safe, legitimate CBD oil for nausea.

FAQs about CBD Oil for Nausea

CBD is legal, as long as it has less than 0.3% THC and comes from hemp (Cannabis Sativa) plants. Congress passed the Hemp Farming Act in 2018 that decriminalized the production and cultivation of hemp plants for commercial utilize. Only the law was passed with specific regulations.

The two main ones are:

  • No hemp products can be sold with a THC content higher than 0.3%
  • Hemp extract derived from cannabis Indica plants (marijuana) is illegal

Is CBD oil good for nausea?

Under current FDA regulations, CBD oil for nausea cannot be sold or marketed as a remedy for anything. Given the evidence presented here and following a consultation with a medical professional, people are free to try CBD oil for nausea if there are no other factors involved, and they do not need further medical attention.

Are there any side effects of using CBD for nausea?

One common side effect of cannabidiol use, in general, is nausea. If using hemp extract provokes nausea, then that is a sign of either:

  • Too-high of a dose
  • Impure or tainted CBD

But it is essential to check with a doctor before taking cannabidiol as a treatment for any particular condition to make sure there are no complications.

Conclusion: Final Thoughts on CBD for Nausea

Cannabinoids have a long history not only of treating nausea and vomiting but a host of other maladies. With its far-reaching effects, it is no wonder that cannabidiol may also have the potential to ease feelings of nausea or prevent emesis. This article detailed how emesis can occur and the ways that CBD for nausea can help.

Readers should first consult a doctor or other medical professional before they start to take hemp extract. And – this cannot be stated enough – if you are regularly experiencing nausea or regular vomiting, it could be a symptom of a severe disorder that needs examining. But, if you are trying CBD oil for non-medical reasons, then the next time you start feeling a rumble in your stomach, a shot of CBD oil might be able to help.

Did you understand the how and why of nausea and vomiting before reading this article? Do you have a better understanding now of how the body reacts to outside influences? Do you think you’ll try to use cannabidiol the next time you are feeling ill? Let us know what you think in the comments section below.

Published: November 19, 2019

Updated: November 22, 2019

Author

Janet Miller

Janet Miller

Janet is a medical specialist with 10 years of experience as a physician and writing passion. She aims to help people and expand humans mindset. Chat with Janet on Twitter @Janet_Miller_MD or via our contact page.

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