Best CBD for Inflammation: The Only Guide You'll Ever Need

Janet Miller

Janet Miller

November 20, 201922 min read

An essential way in which our body responds to injury or infection is inflammation. It signals our immune system to begin fighting the disease and speed up healing. CBD oil can be an effective way of reducing these symptoms.

While over-the-counter painkillers can manage pain, they are harmful and addictive in the long run. It has created a necessity to find an alternative method to reduce and manage inflammation in a safe manner. Over the past decades, scientific studies have found CBD for inflammation has emerged as a natural, safe and non-addictive way to reduce both acute and chronic inflammation. Research shows that best CBD for inflammation works by blocking the body’s pain receptors and working as a powerful antioxidant, which causes inflammation to reduce over time.

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10 Score
EMPE CBD Full Spectrum Hemp Oil Tincture

EMPE CBD Full Spectrum Hemp Oil Tincture

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9.5 Score
Sana Botanicals Pura CBD Tincture Oil

Sana Botanicals Pura CBD Tincture Oil

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9 Score
CBD Massage Oil with essential oils – Rejuvediol™

CBD Massage Oil with essential oils – Rejuvediol™

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The Best CBD Oils for Inflammation


EMPE CBD Full Spectrum Hemp Oil Tincture
10Score

#1 EMPE CBD Full Spectrum Hemp Oil Tincture

Highlights

  • THC-free
  • Organic, smooth taste
  • Infused with Vitamin E
  • Full-spectrum CBD - rich in holistic benefits
  • SIZE/VOLUME

    2.8 oz/ 83 mL

  • TOTAL CBD

    500 mg, 1000mg, 1500 mg, 2000 mg

  • DOSE/SERVING

    One full dropper under tongue. Wait 10-30 seconds before swallowing

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Anti-inflammatory action
    • Pain relief without the psychoactive properties of THC.
    • Quick relief from stress, anxiety and back pain, as per user reviews
  • INGREDIENTS

    Hemp Derived Phytocannabinoids, Organic Hemp Oil, and Vitamin E

This is the best full-spectrum CBD that has organic hemp oil, which gives it a smooth and earthy taste associated with hemp. Infused with the goodness of Vitamin E, it offers the pain-relieving benefits of CBD without the mind-altering effects of THC.
Its broad-spectrum formulation delivers not only the benefits of best CBD but also of terpenes and other natural compounds such as CBN, and CBL found in the hemp plant. While it’s relatively expensive vis-a-vis alternatives of the same concentration, its benefits make up for its price. Being completely THC-free, this oil is also ideal for those who may be worried about failing a drug test.


Sana Botanicals Pura CBD Tincture Oil
9.5Score

#2 Sana Botanicals Pura CBD Tincture Oil

Highlights

  • THC-free
  • Rapid absorption
  • Organic hemp oil
  • 600 mg delivers 40mg/mL
  • SIZE/VOLUME

    30 mL

  • TOTAL CBD

    300mg, 600 mg, 1200 mg

  • DOSE/SERVING

    1ml per dropper, 10mg/ml, 20mg/ml, 40mg/ml

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Chronic pain relief and anti-inflammatory action
    • Improved sleep and restfulness
  • INGREDIENTS

    Hemp extract, organic hemp seed oil

A high concentration CBD oil from Sana Botanicals, this THC-free oil provides a high concentration per dosage, delivering effective relief in a single serving. Available at $ 44.99 for 600mg and $ 69.99 for 1200 mg concentration, its pricing makes it a worthy purchase when compared to other options on the market.

This CBD oil is available in three concentrations ranging from 300mg to 1200 mg. While the 300mg option this CBD is ideal for those suffering from acute discomfort, mild stress, and distraction, the higher doses are a good option for those suffering from chronic inflammation, prolonged stress, and insomnia. Its rapid absorption rate ensures quick relief.


CBD Massage Oil with essential oils – Rejuvediol™
9Score

#3 CBD Massage Oil with essential oils – Rejuvediol™

Highlights

  • Non-sticky formulation
  • Twin benefits of aromatherapy and anti-inflammatory action
  • Infused with essential oils such as primrose, jojoba, sweet almond
  • Non-GMO, cruelty-free, paraben-free
  • SIZE/VOLUME

    200 mL

  • TOTAL CBD

    260 mg

  • DOSE/SERVING

    As per requirement. Take the required amount and warm between palms before massaging onto the desired area.

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Muscle and joint pain relief
    • Aromatherapy and skincare
    • Insomnia
  • INGREDIENTS

    Organic Broad-Spectrum Hemp Oil, Essential oils of sweet almond, Sunflower, Fractionated Coconut, and Jojoba

Rejuvediol has positioned itself as a massage best CBD oil with the twin benefits of inflammation relief and aromatherapy. This broad-spectrum organic hemp oil is non-sticky and delivers its benefits of CBD along with the nourishment of essential oils such as jojoba, sweet almond, and ylang-ylang. Applying it at night before sleeping can improve the quality of your sleep.

The price for a 200ml bottle is $34.99, and it is a great purchase, especially if your source of pain or discomfort is localized in a specific region of your body. Being a topical product, you may have to apply it generously for enough CBD to be absorbed by the skin and its effects to show.


Root Bioscience Full Spectrum Hemp Oil with MCT
8.5Score

#4 Root Bioscience Full Spectrum Hemp Oil with MCT

Highlights

  • The dual benefit of CBD and MCT
  • All-natural products
  • SIZE/VOLUME

    30 mL

  • TOTAL CBD

    500 mg, 1000 mg

  • DOSE/SERVING

    16.67mg/ml, 33.33 mg/ml. Recommended to start with the lowest dosage, ie. 1 ml, and increase if needed

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Athletes looking for increased endurance and performance
    • Relief from pain
    • Improved sleep
    • Acne improvement
    • Anxiety relief
  • INGREDIENTS

    Cannabidiol and other cannabinoids extracted from full spectrum industrial hemp, MCT Oil, Allergen Warning: contains tree nuts (coconut)

The blend of full-spectrum CBD oil with MCT makes this a recommended product for athletes. While cannabidiol relieves inflammation and pain, MCT oil contains fatty acids that help boost metabolism, increase energy levels, and muscle endurance. The stress-relieving action of hemp is also a valuable feature for suffering from performance-related anxiety. It is also the right way for those in physically demanding jobs to improve their quality of sleep, as adequate rest is needed for recovery and muscle repair.

The price for a 500mg concentration is $34.99, this product is one of the most pocket-friendly oils available in the market. Its host of benefits and the high concentration per dosage make it a worthwhile purchase. Important: This product should not be consumed by those who have nut allergies.


Pinnacle CBD Tincture/E-Liquid
8Score

#5 Pinnacle CBD Tincture/E-Liquid

Highlights

  • Less than 0.3 % THC
  • Organic, pesticide-free
  • Can be vaped, applied on the skin or taken sublingually
  • Safe to be used in cooking
  • Mildly sweet
  • SIZE/VOLUME

    15 mL

  • TOTAL CBD

    300mg, 600 mg, 1200 mg

  • DOSE/SERVING

    20mg/ml, 40 mg/ml, 80mg/ml

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Inflammation relief
    • Anxiety and depression
    • Back pain relief
  • INGREDIENTS

    Organic hemp seed oil, vegetable glycerin15 ml

What we find interesting about the Pinnacle CBD oil is that it can be taken in a variety of ways, thanks to its preparation. The CBD oil is equally valid, whether you want to vape it, apply it over the skin, or take it sublingually. It is an organic and pesticide-free formulation and contains less than 0.3% THC.

This full-spectrum CBD oil contains a host of natural compounds that together enhance the benefits of best CBD you consume even more, because of their synergistic effect. While it may be slightly more expensive than its competitors, it may be a good option for those who prefer a product that can be consumed in a variety of ways. Adding it to your food & drink will give it a slightly sweet taste which is pleasant and not overpowering.


Green Roads CBD Oil
7.5Score

#6 Green Roads CBD Oil

Highlights

  • Broad-spectrum CBD oil
  • Available in a variety of concentrations
  • Tested by third-party labs
  • SIZE/VOLUME

    15 mL

  • TOTAL CBD

    100mg, 250mg, 350mg, 550mg

  • DOSE/SERVING

    6.67mg/ml, 16.67mg/ml, 23.33mg/ml, 36.67mg/ml

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • 100 mg concentration ideal for first-time users and beginners
    • Pain and inflammation relief
    • Anxiety and stress relief
  • INGREDIENTS

    Broad Spectrum CBD Oil, Hemp Seed Oil, Kosher-Grade Vegetable, Glycerin, Sunflower Lecithin, Proprietary Terpene Blend

The Green Roads Oil is available in concentrations that range from those suitable for beginners to those effective for long-term users. This CBD oil is Tested in third party labs; the product contains a proprietary blend of terpenes, which amplify its therapeutic properties. While high on quality, this CBD product is priced on the upper side of the spectrum.

Its 550mg variant delivers a potent 37mg per 1 ml dosage. It is quite a substantial dosage for a single serving and can be beneficial to people suffering from chronic pain and conditions. It’s available from 100mg to a 550mg concentration, so buyers have the flexibility to choose the option that is suitable for your situation.


PlusCBD CBD Oil Drops Total Plant Complex
7Score

#7 PlusCBD CBD Oil Drops Total Plant Complex

Highlights

  • Unsweetened and unflavored
  • Fast absorbing formulation
  • Blended with olive oil
  • Can be used for cooking and baking
  • Non-GMO, Vegan-friendly and Gluten-free
  • SIZE/VOLUME

    30 mL

  • TOTAL CBD

    300 mg

  • DOSE/SERVING

    4 mg per serving

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Stress relief
    • Mild pain relief
    • Improved sleep
  • INGREDIENTS

    Hemp Oil (Aerial Plant Parts), Extra Virgin Olive Oil, Quillaja Saponaria

An ideal pick for those who enjoy the natural, earthy flavor of hemp, this unsweetened formulation is made from the brand’s proprietary total plant complex. Blended with extra virgin olive oil, this best full-spectrum CBD oil offers the holistic benefits of the entire hemp plant – from additional compounds, terpenes, fatty acids to naturally found Vitamin E.

Its fast-absorbing action means that the active ingredients enter your bloodstream quickly, providing instant relief. This product is vegan-friendly and non-GMO. An unsweetened and unflavored oil for inflammation is suitable for cooking and baking and can be added to your food and drinks, without altering their taste. At 4mg per serving, this product delivers quite a light dosage with each serving. As a result, it is more suited for beginners and first-time users rather than those suffering from chronic and more severe conditions.


Biotech CBD Topical Cream
6.5Score

#8 Biotech CBD Topical Cream

Highlights

  • Less than 0.3% THC
  • High concentration formula
  • Infused with menthol and tea tree
  • SIZE/VOLUME

    140 g

  • TOTAL CBD

    1000 mg

  • DOSE/SERVING

    Apply the required amount topically over the desired skin area

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Post-workout recovery
    • Inflammatory and pain relief
    • Stress and anxiety relief
  • INGREDIENTS

    Industrial Hemp Cannabidiol (CBD), Menthol, Tea Tree Oil, Tocopherol Acetate (Vitamin E)

Blended with menthol and tea tree oil, this topical best CBD cream for inflammation is a high-concentration formulation that’s a good value for money for long-term users. With less than 0.3% THC, this is a full-spectrum CBD cream for inflammation that’s easy to apply. It’s ideal for post-workout recovery as well as inflammation relief. It’s price point and benefits makes it a candidate for the best CBD cream for inflammation in the market.

This best CBD cream for inflammation is infused with aloe vera powder, Vitamin E, tea tree oil, and method for added benefits. Being a topical cream, you may have to apply a more generous amount over the skin for a noticeable effect. It is because of the skin’s lesser permeability vis-a-vis sublingual (under the tongue) absorption in the case of tinctures.


HempCeutix Pure CBD Tincture Oil
6Score

#9 HempCeutix Pure CBD Tincture Oil

Highlights

  • Available in various concentrations
  • Can be added while cooking
  • Safe for use by pets
  • SIZE/VOLUME

    50 mL

  • TOTAL CBD

    250mg, 750mg, 1500mg, 3000mg, 6000mg

  • DOSE/SERVING

    5mg/ml, 15mg/ml, 30mg/ml, 60mg/ml, 120mg/ml

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Stress control and relaxation
    • Inflammation relief
    • Improved sleep
  • INGREDIENTS

    Extra virgin olive oil, virgin Cannabis Sativa oil

Available in a spectrum of concentrations, the Hempceutix oil is blended with extra virgin olive oil and can be used for cooking and baking as well. Safe for use even for your pets, it’s ideal for relief from chronic inflammation and promotes improved sleep and relaxation.

Priced at a pocket-friendly $36.99 for 750mg with a moderate dosage of 15mg/ml, we’d say it hits the sweet spot between effectiveness and value. It’s available in a range of concentrations – from 250mg up to a massive 6000mg. This way, it appears to cater to a host of users – from beginners to those suffering from chronic conditions.


Empe CBD Muscle and Joint Cream
5.5Score

#10 Empe CBD Muscle and Joint Cream

Highlights

  • Rapid absorption
  • Blended with menthol and natural hemp seed oil
  • Ideal for joint pains
  • SIZE/VOLUME

    97.5mL

  • TOTAL CBD

    250 mg

  • DOSE/SERVING

    2.56mg/mL

  • TEST RESULTS

    Available on site

  • GOOD FOR

    • Instant pain relief
    • Pre and post-workout recovery
    • Joint and back pain relief
    • Muscle cramps relief
  • INGREDIENTS

    Menthol, Cannabidiol-infused Hemp Oil (Derived from Industrial Hemp), Aloe Vera Gel, Tocopherol Acetate (Vitamin E)

In the case of inflammation in a localized area, a rapid absorption formulation can provide fast relief. This muscle and joint lotion for inflammation are blended with menthol, tea tree oil, and natural hemp seed oil. Ideal for application both pre and post-workout, it can provide instant relief from soreness and pain in a localized area. This formulation also acts quickly on sports-related stiffness, muscle spasms, and injuries.

With a 250mg concentration and a dosage of roughly 2.56mg/ml, this is a relatively light formulation. As a result, you’d have to apply a generous amount multiple times a day to see results. Its competitive price point has been a high-selling lotion for joint pain relief.


What Is Inflammation, and When Is It Bad for the Body?

Before we learn about the best CBD for inflammation, let’s understand what exactly it is and what it does to our body. To put it simply, it is our body’s response to an injury or an irritant that’s entered the body. It is a way by which our body signals the immune system to start fighting its cause.

Some symptoms include redness, swelling, pain, and loss of function (for. Eg. not being able to smell correct when you have a cold).

There are two types of inflammation: Acute (short-term) and chronic (long-term). While in most cases, it is a low condition that can stir our body into action to fight back, in some cases, it can be a long term phenomenon.

Chronic inflammation can happen in infections that are left untreated and also in cases such as rheumatoid arthritis, psoriasis, and cancer. Such conditions can be a source of constant discomfort whose pain can last for years and decades.

What Does Best CBD for Inflammation Do?

Over the past few decades, there has been a growing body of research that is already confirming what had so far been considered hearsay: that best CBD has clear and potent anti-inflammatory properties.
Studies have shown that using CBD for inflammation has an immunosuppressant action on the body. This makes its use very beneficial in reducing chronic inflammation as well as treating autoimmune disorders such as allergic asthma and Type 1 Diabetes.

How CBD Reduces Inflammation?

There are three broad ways in which CBD for inflammation reduces it in our bodies:

  • TRPV1 receptors: The human body has receptors known as TRPV1 that are responsible for mediating pain and inflammation, among other properties. By binding to these receptors and desensitizing them, best CBD reduces the inflammatory response in our body.
  • Glycine receptors: These receptors are also responsible for transmitting pain signals from the spinal cord to the brain. Best CBD for inflammation works by interacting with the body’s glycine receptors and blocking their ability to transmit pain signals.
  • Reducing oxidative stress: Best CBD for inflammation has antioxidant properties, which combats free radicals and protects our cells and tissues from damage.

How Long for CBD Oil to Reduce Inflammation?

The amount of time it takes for a best CBD oil for inflammation to be absorbed in your system depends primarily on the method of consuming CBD for inflammation. In most cases, vaping is the quickest way of consuming it, with the active ingredient being absorbed into the bloodstream within ten minutes of taking it. Consuming CBD for inflammation sublingually or applying it topically can show results anywhere between 45 minutes to up to an hour. On the other hand, digesting CBD for inflammation by mixing it with a food or beverage can take the longest, up to two hours.

CBD for inflammation works by blocking individual body’s pain receptors in our body, and by protecting our tissues from oxidative damage. In this case, inflammation becomes attenuated. Also, the best CBD for inflammation affects microglial cells and thereby reduces neuroinflammatory mechanisms.

Buyer’s Guide

CBD for Inflammation: Athletes

Being an athlete means having to deal with frequent muscle soreness, inflammation, and injury. If left untreated, these conditions can also cause anxiety and performance-related stress. The benefits of best CBD for inflammation in all the above cases have been well documented, which makes it a better choice vis-a-vis over the counter painkillers that may have significant side effects if taken long term.

CBD for Inflammation: Joint Pain

Chronic joint pain in cases such as arthritis can be a debilitating lifelong condition. In such cases, the use of best CBD for inflammation is effective in reducing inflammation and managing joint pain. A study conducted in 2017 on rats demonstrated how effective it could prevent nerve damage in the case of joint pain.

CBD for Inflammation: Neuroinflammation and Alzheimer’s Disease

You may have heard of Alzheimer’s disease and its damaging effects on a person’s memory and abilities. Alzheimer’s disease is mainly caused by inflammation in the brain’s nerve tissues as a response to the build-up of specific proteins in the brain. While its direct impact on treating Alzheimer’s has not been proven, studies have shown how best CBD for inflammation can protect the brain from nerve damage, oxidative stress, while also promoting nerve repair and growth.

CBD for Inflammation: Cancer Prevention

Several studies have documented the link between chronic inflammation and cancer for a long time. While direct research is yet to be done to understand if CBD can have a direct impact on preventing certain diseases, their role in reducing chronic inflammation has been demonstrated across a number of studies. Since inflammatory conditions and cancer are undeniably linked, best CBD for inflammation can treat and manage the disease, which, if unchecked, could potentially lead to cancer development.

How to Use CBD Oil for Inflammation?

There are several ways by which you can use best CBD oil for inflammation. You can decide the method based on what feels the most comfortable for you.

How to Consume CBD for Inflammation?

CBD for inflammation can be consumed in a variety of ways to reduce inflammation, some of which are as follows:

  • Sublingual: Sublingual oils are formulated to be absorbed under the tongue. It is a quick and direct way of taking best CBD for inflammation, as the product does not have to be digested fully for its results to show. Tinctures made by soaking the cannabis plant in alcohol or oils, and they are ideal for sublingual use.
  • Topical: Creams and topicals are designed to be absorbed directly from the skin. Best CBD products for inflammation are ideal if the condition is localized in a specific area of the body. Creams, salves, and lotions specially formulated for this purpose can be applied directly onto the skin. Since our skin’s permeability is lesser than areas such as our tongues, we may need a higher concentration product and have to apply it generously for the desired impact.
  • Inhalation: You can inhale oil by using them in a vape pen, and this allows the compound to go directly into your bloodstream. As a result, vaping can make you absorb anywhere between 35-50% within the first ten minutes. However, the exact impact of vaping on the lungs is still being studied, so it may be better to use other alternative means.
  • Edibles: If you’re okay with a slightly slower pace of absorption, then consuming edibles will be a useful option as well. Some options on the market are ideal for cooking and baking. Once eaten best CBD for inflammation, it takes up to two hours for the effects to show, and you can expect about 20 to 30% absorption rate in this method.

What Is the Best Dosage of CBD Oil for Inflammation?

To put it simply, there is no single correct dosage of the best CBD for inflammation that can work for everyone. The dosage can vary greatly from person to person and is dependent on their specific needs and conditions.

  • For cases with mild inflammation that is acute (temporary) in nature, a 10mg concentration may be effective.
  • In chronic and serious cases such as rheumatoid arthritis or cancer, a higher dosage of anywhere between 20mg to even 1000mg per day may be needed.

It is recommended to start off with a small dosage, to begin with, and to slowly increase the dosage with time till you achieve the desired relief for your condition.

How Long to Take Best CBD for Inflammation?

In the case of short term inflammation, best CBD use can be discontinued as soon as the injury or infection in question clears up. However, in the case of chronic inflammation, you could choose to use it for as long as needed to manage the pain and discomfort. This could be weeks, months or even years in some cases.

FAQ

Is There Any Scientific Evidence of Using Best CBD for Inflammation and Pain Relief?

Multiple studies conducted on animal models over the years have demonstrated the anti-inflammatory and pain-relieving properties of best CBD. Cannabinoids have shown to have protective and anti-arthritic properties in a study on animal models with rheumatoid arthritis. A study done in 2012 on the relation between cannabinoids and muscular pain found that it decreases the transmission of pain response in both acute as well as chronic inflammatory conditions.

The legality of using best CBD is unclear for a variety of reasons. While the sale and use of Marijuana have been illegal since the Marijuana tax act of 1937, some US states have made it legal for purely medical use. A new ruling in 2016 states that any CBD product that contains other cannabinoids is illegal, while a pure extract without any other cannabinoids can potentially be legal for use. Moreover, the new farm bill legalized the cultivation of hemp, making the situation even more complex. The best way to know if CBD is legal in your area is to do research on the local laws in your geographical location and be aware of the list of ingredients in your product.

Is CBD for Inflammation Safe?

Even though there is continued research needed to understand the effects and uses of CBD fully, current studies show it to be a very low-risk way to manage inflammation. In fact, The National Institute on Drug Abuse states that CBD appears to be a low-risk drug with no addictive effects and multiple therapeutic uses.

Are There Any Side Effects of Using CBD for Inflammation?

A study done in 2017 to understand the side effects of best CBD for inflammation concluded that it has a very low-risk profile vis-a-vis other medication. However, further research is needed to understand how it interacts with other drugs.

CBD Oil for Inflammation: Final Thoughts

If you or anyone you know suffers from inflammation, then you’re well aware of its debilitating effects on daily life. In such cases, best CBD oil has shown promise as a natural, safe and non-addictive way to not only manage but also reduce inflammation in the long run.

By blocking our body’s pain receptors as well as reducing the oxidative stress on the tissues, the best CBD oil plays a protective and anti-inflammatory role in our body in the long run. Studies have shown cannabinoids to not only reduce nerve damage in case of injuries but also help in nerve repair and growth.

What has been your experience with the best CBD oils? We’d love to whether and how it has helped you. Feel free to comment or ask questions in the comment box below.

Published: November 20, 2019

Updated: November 28, 2019

Author

Janet Miller

Janet Miller

Janet is a medical specialist with 10 years of experience as a physician and writing passion. She aims to help people and expand humans mindset. Chat with Janet on Twitter @Janet_Miller_MD or via our contact page.

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